Development and Validation of Hptlc Method for Simultaneous Determination of Rosuvastatin Calcium and Aspirin in Its Pure and Pharmaceutical Dosage Form
نویسندگان
چکیده
Development and validation of simple, rapid, precise, accurate and sensitive HPTLC method for the simultaneous estimation of Rosuvastatin calcium and Aspirin in bulk and in capsule dosage form. The mobile phase consisting of Ethyl acetate:Toluene:Glacial acetic acid (6:3:1 v/v/v) and wavelength of detection 240nm was used . The linearity of the calibration curves for Rosuvastatin calcium and Aspirin in the desired concentration range is good (r2 =0.998) by this method. The result of analysis has been validated statistically and recovery study confirmed the accuracy of proposed method. This method was successfully applied to the routine determination of these drugs in bulk and in its pharmaceutical dosage form.
منابع مشابه
Development and Validation of UV Spectrophotometric Method for Simultaneous Determination of Rosuvastatin Calcium and Aspirin in its Pure and Pharmaceutical Dosage Forms
Development and validation of two simple, rapid, precise, accurate and sensitive UV spectrophotometric methods for the simultaneous estimation of Rosuvastatin calcium and Aspirin in bulk and in capsule dosage form. The methods are based on the measurement of absorbance of Rosuvastatin calcium and Aspirin at 241nm and 296nm respectively. The linearity of the calibration curves for Rosuvastatin c...
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